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Although plasma levels of sildenafil at 24 hours post dose are much lower than at peak concentration, it is unknown whether nitrates can be safely co-administered at this time point [see DOSAGE AND ADMINISTRATION, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY]. Due to age-differences in plasma protein binding, the corresponding increase in the AUC of free (unbound) sildenafil and its active N-desmethyl metabolite were 45% and 57%, respectively [see CLINICAL PHARMACOLOGY].

The recommended initial dose for once daily Cialis treatment is 2. In the following patients: age > 65 years, hepatic impairment (e.g., cirrhosis), severe renal impairment (e.g., creatinine clearance < 30 mL/min), and concomitant use of erythromycin or strong CYP3A4 inhibitors, plasma levels of sildenafil at 24 hours post dose have been found to be 3 to 8 times higher than those seen in healthy volunteers. He can't seem to keep an erection,half way through it'll go down. For more information, please consult with your healthcare provider. A: Viagra (sildenafil) is a prescription medication used to treat erectile dysfunction. Néanmoins, avant de faire usage de ce médicament, il est recommandé de lire très attentivement toutes les indications médicales, un mauvais usage pourrait entraîner des complications.

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The patent for Viagra (sildenafil) will not expire until 2012; therefore, no generic, less expensive form is currently available. Viagra’s effects typically last for between four and six hours, and it should not be taken unless you intend to have sex. McLeod AL, McKenna CJ, Northridge DB "Myocardial infarction following the combined recreational use of Viagra and cannabis." Clin Cardiol 25 (2002): 133-4 17.

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The pharmacokinetics of sildenafil in patients with severely impaired hepatic function (Child-Pugh Class C) have not been studied. Viagra was the harbinger of things to come in the form of the pharmacology of aging and sexuality (sexual medicine is in expansion mode post-Viagra). Diary data in two of the studies (n=178) showed rates of successful intercourse per attempt of 70% for VIAGRA and 29% for placebo. A: Viagra (sildenafil) is used for the treatment of erectile dysfunction.

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This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Another thing to consider is that sexual activity is associated with a degree of cardiac risk. If possible, use one pharmacy for all your prescription medications and over-the-counter products. Read More I experienced the side effects I was told could happen, worse cramps and heavier bleeding. Always keep a current list of the drugs and supplements you take and review it with your healthcare providers and your pharmacist. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum. It is an expensive medication and will not be available as a generic for a few more years.