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Some were worried about how it actually worked and the possible consequences. A: Viagra (sildenafil) is classified as a phosphodiesterase 5 enzyme inhibitor. Dilantin could increase the metabolism of the Depakote. You will not get an erection just by taking this medicine. Your physician is best able to determine if Viagra is appropriate for you or not. Individuals taking alpha-blockers should make sure they take Viagra at least 4 hours before or after taking alpha-blockers.
An evaluation of visual function at doses up to twice the maximum recommended dose revealed no effects of VIAGRA on visual acuity, intraocular pressure, or pupillometry. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.
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Dilantin could increase the metabolism of the Depakote. Egan R, Pomeranz H "Sildenafil (Viagra) associated anterior ischemic optic neuropathy." Arch Ophthalmol 118 (2000): 291-2 42. Effects of VIAGRA on Sperm There was no effect on sperm motility or morphology after single 100 mg oral doses of VIAGRA in healthy volunteers. There is also a possibility of a drug interaction between the Dilantin and the Depakote. Be very cautious about purchasing a drug claiming to be the generic.
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Viagra exhibits no therapeutic responses in the absence of sexual stimulation. At doses above the recommended dose range, adverse reactions were similar to those detailed in Table 1 below but generally were reported more frequently. In some of the cases, medical conditions and other factors were reported that may have also played a role in the otologic adverse events. The side effects included headaches, dizziness and just being tired. The reaction of anaphylaxia with desensibilization on guinea pigs and the method of double diffusion in agar gel were used to study the antigenic composition of the rat skeletal muscles 3, 7 and 30 days after their cross sections were connected with polyurethane glue and silk. This can result in the drug building up to toxic levels in the body.
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Patti Brown, PharmD Q: Is it safe to take Viagra? This is compared to a 19 percent positive response for those taking a placebo. Therefore your overall cardiovascular status needs to be considered when you contemplate taking Viagra. This will need to be replicated in additional trials for it to be approved for postmenopausal women. It's a way for men to deny that they are past their sexual peak. However, it can have a serious interaction with nitrates. Drug Interactions DRUG INTERACTIONS Nitrates Administration of VIAGRA with nitric oxide donors such as organic nitrates or organic nitrites in any form is contraindicated. Michelle McDermott, RPh, PharmD Q: I take two drugs to control my seizure disorder caused by a car accident (Depakote and Dilantin). Grapefruit and grapefruit juice should be avoided, as enzymes in the fruit can stop Viagra from working altogether. However, since higher plasma levels may increase the incidence of adverse reactions, a starting dose of 25 mg should be considered in older subjects due to the higher systemic exposure [see DOSAGE AND ADMINISTRATION]. In Vivo Studies No significant interactions were shown with tolbutamide (250 mg) or warfarin (40 mg), both of which are metabolized by CYP2C9. Allergy warning Sildenafil can cause a severe allergic reaction. Other common side effects of Viagra include warmth or redness in your face, neck, or chest; stuffy nose; headache; upset stomach; and back pain.
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