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Efficacy Results from Controlled Clinical Studies The effect on one of the major end points, maintenance of erections after penetration, is shown in Figure 6, for the pooled results of 5 fixed-dose, dose-response studies of greater than one month duration, showing response according to baseline function. The most common side effects of VIAGRA: headache; flushing; upset stomach; abnormal vision, such as changes in color vision (such as having a blue color tinge) and blurred vision; stuffy or runny nose; back pain; muscle pain; nausea; dizziness; rash.

Matt Curley, PharmD Q: Is there a generic for Viagra? Others were reported to have occurred hours to days after the use of VIAGRA and sexual activity. Sometimes, nitrates are also given on a daily basis, once or twice a day.

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Sudden Hearing Loss Physicians should advise patients to stop taking PDE5 inhibitors, including VIAGRA, and seek prompt medical attention in the event of sudden decrease or loss of hearing. What are the long-term implications for a society that has Viagra in its drug arsenal? Effects On The Eye Physicians should advise patients to stop use of all phosphodiesterase type 5 (PDE5) inhibitors, including VIAGRA, and seek medical attention in the event of a sudden loss of vision in one or both eyes.

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Patients should always ask their doctors for medical advice about adverse events. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum.

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You may have used, or use, other erectile dysfunctions including Viagra, Cialis and Levitra. It is not possible to determine whether these events are related directly to VIAGRA, to sexual activity, to the patient's underlying cardiovascular disease, to a combination of these factors, or to other factors [see WARNINGS AND PRECAUTIONS and PATIENT INFORMATION]. VIAGRA may affect the way other medicines work, and other medicines may affect the way VIAGRA works, causing side effects. This can result in the drug building up to toxic levels in the body. In these studies, side effects occurring in a group of people taking the drug are documented and compared to those that occur in another group not taking the medicine. In addition to human corpus cavernosum smooth muscle, PDE5 is also found in other tissues including platelets, vascular and visceral smooth muscle, and skeletal muscle, brain, heart, liver, kidney, lung, pancreas, prostate, bladder, testis, and seminal vesicle. Nitric oxide allows the smooth muscles inside the penis to relax, promoting more blood flow to the area during sexual arousal or stimulation. This includes nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket).