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Once you've swallowed one pill, it may take up to 60 minutes to take full effect and this may last for up to 4 hours. One of the less common side effects associated with Viagra is a medical emergency known as priapism. Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment Of Fertility Carcinogenesis Sildenafil was not carcinogenic when administered to rats for 24 months at a dose resulting in total systemic drug exposure (AUCs) for unbound sildenafil and its major metabolite of 29-and 42-times, for male and female rats, respectively, the exposures observed in human males given the Maximum Recommended Human Dose (MRHD) of 100 mg. If these occur, you should contact your healthcare provider. Arruda-Olson AM, Pellikka PA "Appropriate use of exercise testing prior to administration of drugs for treatment of erectile dysfunction." Herz 28 (2003): 291-7 9.
According to the prescribing information, some of the possible side effects associated with Viagra treatment include headache, flushing, dyspepsia (upset stomach, indigestion), nasal congestion, urinary tract infections, abnormal vision, diarrhea, dizziness and rash. Interactions People with HIV who take protease inhibitors should discuss using Viagra with their doctors.
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The AUC of the active metabolite, N-desmethyl sildenafil, was increased 62% by loop and potassium-sparing diuretics and 102% by nonspecific beta-blockers. Maximum dosage: 20 mg, taken three times per day about 4 to 6 hours apart. Conti CR, Pepine CJ, Sweeney M "Efficacy and safety of sildenafil citrate in the treatment of erectile dysfunction in patients with ischemic heart disease." Am J Cardiol 83 (1999): c29-34 7. A: Viagra (sildenafil) (//www.everydayhealth.com/drugs/viagra) is a phosphodiesterase type 5 inhibitor (PDE5).
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The device is lightweight, handheld, and battery-powered, and it emits x-ray radiation from the tip of a probe 3 mm in diameter by 10 cm in length. Tell your doctor about all your current medicines and any you start or stop using, especially: drugs to treat high blood pressure or a prostate disorder; an antibiotic - clarithromycin, erythromycin, or telithromycin; antifungal medicine - ketoconazole or itraconazole; or medicine to treat HIV/AIDS - atazanavir, indinavir, ritonavir, or saquinavir; nitrates; medications used to treat pulmonary artery hypertension.
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Binding Characteristics Studies in vitro have shown that sildenafil is selective for PDE5. Viagra was developed to help men with erectile dysfunction. In some of the cases, medical conditions and other factors were reported that may have also played a role in the otologic adverse events. Consult your physician or healthcare provider for specific recommendations on potential alternatives to Viagra treatment. Storage And Handling VIAGRA (sildenafil citrate) is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to the nominally indicated amount of sildenafil and debossed on the obverse and reverse sides as follows: Recommended Storage Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature]. It works by allowing increased blood flow to the penis, which causes an erection.
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