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Efficacy Results from Controlled Clinical Studies The effect on one of the major end points, maintenance of erections after penetration, is shown in Figure 6, for the pooled results of 5 fixed-dose, dose-response studies of greater than one month duration, showing response according to baseline function. Vobig MA "Retinal side-effects of sildenafil." Lancet 353 (1999): 1442 40. Sildenafil was not carcinogenic when administered to mice for 18-21 months at dosages up to the Maximum Tolerated Dose (MTD) of 10 mg/kg/day, approximately 0.

Bosch X "Sildenafil's effects extended to additional organs." Lancet 355 (2000): 631 31. Therefore, inhibitors of these isoenzymes may reduce sildenafil clearance and inducers of these isoenzymes may increase sildenafil clearance.

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Because sexual problems are a prime reason patients give for stopping the antidepressants, experts think it is important to find a way to relieve the sexual problems. The dose of Viagra may be increased to 100 mg or decreased to 25 mg based on therapeutic response and tolerability.

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Travel When traveling with your medication: Always carry your medication with you. The pharmacokinetics of sildenafil are dose-proportional over the recommended dose range. Cialis (tadalafil) is known as the "weekend pill," because it lasts approximately 17 to 36 hours.

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He or she will do a physical examination, look at your current medications, and will decide which medication you would benefit from. Read More Well I took 1 or 2 pills of wellbutrin and didn't like the side effects (i think the side effects was actually just the stress), Anyway I didn't take any medication and dec passed then jan passed and they all just went away. The maximum recommended dose is 100 mg with a maximum recommended frequency of administration of once daily. Cardiovascular Considerations Physicians should discuss with patients the potential cardiac risk of sexual activity in patients with preexisting cardiovascular risk factors.