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There are no adequate and well-controlled studies of this drug in pregnant women. Reduced testosterone levels combined with higher levels of estrogen may feminize your body. You may take it up to 4 hours before sexual activity. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Sildenafil is approximately 4,000-fold more selective for PDE5 compared to PDE3.

Sildenafil has no direct relaxant effect on isolated human corpus cavernosum. In the course of my research I found that Pfizer had consulted with quite a few experts about possible litigation down the line regarding Viagra.

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PadmaNathan H, Steers WD, Wicker PA "Efficacy and safety of oral sildenafil in the treatment of erectile dysfunction: A double-blind, placebo-controlled study of 329 patients." Int J Clin Pract 52 (1998): 375-9 35. A: Viagra (sildenafil) should not be used in patients also using a nitrate drug for chest pain or heart problems. It’s linked with the development of female sexual characteristics and reproduction. Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level.

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Egan RA, Pomeranz H "Transient ischemic attack an stroke associated with sildenafil (Viagra) use." Neurology 59 (2002): 293-4 20. Always carry the original prescription-labeled container with you. Using colony formation in soft agar as a measure of full transformation, we report here that R- cells can be transformed by v-src, although they still cannot be transformed by the activated c-src527 (mutation at tyrosine 527 to phenylalanine), which readily transforms mouse embryo cells with a wild-type number of IGF-I receptors (W cells).

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It is important to avoid nitroglycerin while taking these medications, but work is being done to develop a similar medication that can be taken with nitroglycerin. I am a 61-year-old male who had a prostate operation two years ago. He aslo has a problem keeping an erection and we both think that he needs Viagra or something??? Zusman RM, Morales A, Glasser DB, Osterloh IH "Overall cardiovascular profile of sildenafil citrate." Am J Cardiol 83 (1999): c35-44 22. The typical recommended starting dose of Levitra is 10 mg and dosages can range from 5 mg to 20 mg depending on desired response and adverse reactions.