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When the drug leaves the body, it does so by being filtered out through a specific pathway in the liver. A: Viagra (sildenafil), is a for erectile dysfunction and for pulmonary arterial hypertension, and may be split, but the shape of the table is not easy to cut. Effect of VIAGRA on Blood Pressure When Co-administered with Anti-hypertensives When VIAGRA 100 mg oral was co-administered with amlodipine, 5 mg or 10 mg oral, to hypertensive patients, the mean additional reduction on supine blood pressure was 8 mmHg systolic and 7 mmHg diastolic.

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There were no severe adverse events potentially related to blood pressure and no episodes of syncope reported in this study. You may report side effects to FDA at 1800-FDA-1088.

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Michelle McDermott, RPh, PharmD Q: I take two drugs to control my seizure disorder caused by a car accident (Depakote and Dilantin). Both sildenafil and the metabolite have terminal half lives of about 4 hours. The medication was first developed in England for used as an blood pressure reducer, but it worked better for penile dysfunction, so the makers decided to market it for that. The concomitant use of erythromycin or strong CYP3A4 inhibitors (e.g., saquinavir, ketoconazole, itraconazole) as well as the nonspecific CYP inhibitor, cimetidine, is associated with increased plasma levels of sildenafil [see DOSAGE AND ADMINISTRATION]. Is there such a thing as generic sildenafil citrate? Call your doctor for medical advice about side effects. At 24 hours the plasma levels of sildenafil were still approximately 200 ng/mL, compared to approximately 5 ng/mL when sildenafil was dosed alone.