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A: I do not know what strength Viagra (sildenafil) you take, but your physician may want to increase the strength you take. It is eliminated predominantly by hepatic metabolism (mainly CYP3A4) and is converted to an active metabolite with properties similar to the parent, sildenafil. Israilov S, Baniel J, Shmueli J, et al. "Treatment program for erectile dysfunction in patients with cardiovascular diseases." Am J Cardiol 93 (2004): 689-93 6.

If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took VIAGRA. Further information Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Viagra only for the indication prescribed.Johns Hopkins Medicine Office of Corporate Communications Media contact: David March 410-955-1534; dmarch1@jhmi.edu October 24, 2005 VIAGRA BLUNTS EFFECTS OF STRESS ON THE HUMAN HEART Sildenafil citrate (Viagra), a drug used to treat erectile dysfunction (ED) in millions of men, reduces the stimulatory effects of hormonal stress on the heart by half, according to results of a new study by researchers at Johns Hopkins.  While sildenafil is more widely known for helping genital blood vessels expand to maintain an erection and, more recently, as a treatment for pulmonary hypertension, it has been thought to have little direct effect on the human heart. The results suggest an approximate 2 fold increase in the risk of NAION within 5 half-lives of PDE5 inhibitor use.

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Priapism is a painful erection lasting for more than four hours which requires immediate medical attention and treatment. Clinical data have shown that co-administration with saquinavir or erythromycin increased plasma levels of sildenafil by about 3 fold [see DRUG INTERACTIONS and CLINICAL PHARMACOLOGY].

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The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. A: Viagra (sildenafil) is classified as a phosphodiesterase 5 enzyme inhibitor. Increased side effects can include low blood pressure, dizziness, or vision problems. Increased side effects can include a drop in blood pressure, or fainting. Sildenafil only works for ED if you’re sexually aroused.

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Generic drugs usually cost less than the brand-name version. If you have liver or kidney problems, Viagra’s effects could last for longer, although it might not be safe to take Viagra with these conditions. This helps men with ED get and keep an erection hard enough for sex when sexually stimulated. It is possible to enjoy alcohol when using Viagra, but remember to drink moderate amounts only. Read More This, in turn, affects the blood pressure and can possibly contribute to the development of an abnormal heart rate, a stroke or a heart attack. If the medication is losing its effectiveness for you, you may want to consult your doctor for an alternative. The new measures tend to extend the role of social security programs through providing a greater proportion of the population with more comprehensive protection and setting higher benefit rates to replace income lost because of old age, disability, sickness, work injury, unemployment, or death. The next day, he slept most of the day in a reclining chair. However, since higher plasma levels may increase the incidence of adverse reactions, a starting dose of 25 mg should be considered in older subjects due to the higher systemic exposure [see DOSAGE AND ADMINISTRATION]. Erectile dysfunction was attributed to organic (58%; generally not characterized, but including diabetes and excluding spinal cord injury), psychogenic (17%), or mixed (24%) etiologies. If these occur, you should contact your healthcare provider. John Jamelske, the 67-year-old man who held a number of young women captive as sexual slaves in an underground bunker, took Viagra. If you have these symptoms, stop taking VIAGRA and contact a doctor right away Before you take VIAGRA, tell your healthcare provider if you: Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.