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Viagra begins to work within about an hour and the effects can last for up to four hours. In the following patients: age > 65 years, hepatic impairment (e.g., cirrhosis), severe renal impairment (e.g., creatinine clearance < 30 mL/min), and concomitant use of erythromycin or strong CYP3A4 inhibitors, plasma levels of sildenafil at 24 hours post dose have been found to be 3 to 8 times higher than those seen in healthy volunteers.

Combination With Other PDE5 Inhibitors Or Other Erectile Dysfunction Therapies The safety and efficacy of combinations of VIAGRA with other PDE5 Inhibitors, including REVATIO or other pulmonary arterial hypertension (PAH) treatments containing sildenafil, or other treatments for erectile dysfunction have not been studied. Previous reports have shown that Viagra could trigger potentially dangerous drops in blood pressure in these men. It appears unlikely that this drug will harm a pregnancy. It also alleviates time and energy on the NHS and other doctor's services.

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Therefore the medication should be used with caution by patients who have left ventricular outflow obstruction and should only be used by patients who are hemodynamically stable prior to starting therapy. Prolonged Erection And Priapism Prolonged erection greater than 4 hours and priapism (painful erections greater than 6 hours in duration) have been reported infrequently since market approval of VIAGRA. It was originally used for ph but they found that one of the side effects helped with ed.

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Michelle McDermott, PharmD Q: I have diabetes and a replaced valve. If there is no sexual stimulation, viagra will not work. Priapism may lead to permanent damage if left untreated, including the permanent loss of ability to have an erection. About 15 women who took the medication have not yet given birth. If you experience a continual and prolonged erection (exceeding 4 hours) otherwise known as 'priapism', you must seek medical attention.

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Chocoholic Miss DubaiForums 2005 Posts: 12833 Reply Re: Viagra - HELP! After the FDA determines that a drug is safe to be marketed, the pharmaceutical company has a patent on that drug for 10 to 13 years. Increased fetal weights to normal values, compared with untreated hypertensive offspring whose weights were reduced by more than 20 percent. "This observation also supports an effect on uterine blood flow since it well known that restriction of uterine blood flow during pregnancy is associated with reduced fetal weight, which is a serious clinical problem," Osol adds. "Third, and most surprisingly, Viagra completely prevented fetal resorption, or fetal mortality. Subjects who had successfully completed the previous doxazosin interaction study (using VIAGRA 50 mg), including no significant hemodynamic adverse events, were allowed to skip dose period 1. Your body is reacting unfavorably and that can endanger your overall health.How well Viagra works, or how long it lasts for, depends on a number of things. Taking Viagra with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack. This can be harmful or prevent the drug from working well. Most medications can be cut in two if they are not extended release, but you should always check with your doctor or pharmacist, as the guideline is not always true. When getting a prescription from a doctor, you may want to ask that they write the prescription for a higher dose and have you cut it, to avoid confusion.