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When the Dutch trial was stopped, roughly half of 183 pregnant women involved in the study were taking Sildenafil, participating hospital Amsterdam University's Academic Medical Centre (AMC) said. By inhibiting phosphodiesterase, Viagra enhances the effect of nitric oxide allowing for smooth muscle relaxation and increasing blood flow to specific areas of the body in the presence of sexual arousal or stimulation. CONTRAINDICATIONS Nitrates Consistent with its known effects on the nitric oxide/cGMP pathway [see CLINICAL PHARMACOLOGY], VIAGRA was shown to potentiate the hypotensive effects of nitrates, and its administration to patients who are using nitric oxide donors such as organic nitrates or organic nitrites in any form either regularly and/or intermittently is therefore contraindicated.

The dosage for Cialis for once daily use may be increased to 5 mg if necessary. If you get any side effects, talk to your doctor or pharmacist. Some Americans are married to a newfound wonder drug and don't know how to get a divorce. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.What is sildenafil, and how does it work (mechanism of action)? What can I do to get more effective help from Viagra?

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The next day, he slept most of the day in a reclining chair. Over 550 patients were treated for longer than one year. With treatment with Cialis, improvement in erectile function is possible for anywhere from 24 to 36 hours after administration of a dose, significantly longer than with Viagra. Sildenafil enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum.

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A: Viagra (sildenafil) is indicated for use in the treatment of erectile dysfunction in men. A starting oral dose of 25 mg should be considered in those patients [see DOSAGE AND ADMINISTRATION]. Call your doctor at once if you have: ringing in your ears, or sudden hearing loss; irregular heartbeat; swelling in your hands, ankles, or feet; shortness of breath; seizure (convulsions); or a light-headed feeling, like you might pass out.

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Interaction With Other Drugs Viagra side effects may be increased by certain other medications – it is not recommended to mix some medicines. This can cause your body to process drugs more slowly. A second study discussed in the review found that both pre- and postmenopausal women reported no significant positive responses when using Viagra. There are some less common side effects that affect 2-3% of men. May 17, 2008 english^night wrote:Hello, I am new member and new in this country... and I have been looking around the Internet but no hope for any reputed online source that I can buy VIAGRA from? Study 1: VIAGRA with Doxazosin In the first study, a single oral dose of VIAGRA 100 mg or matching placebo was administered in a 2-period crossover design to 4 generally healthy males with benign prostatic hyperplasia (BPH). Arnold, have stated in the Annals of Pharmacotherapy that "the drug has been suggested as a contributing factor in 22 cases involving aggression, 13 involving rape, and 6 involving murder." Clearly, Viagra is linked to violence against women. Those suffering from liver disease or kidney disease which requires dialysis treatment are also advised to avoid taking Viagra. It is not possible to determine whether these events are related directly to VIAGRA, to sexual activity, to the patient's underlying cardiovascular disease, to a combination of these factors, or to other factors [see WARNINGS AND PRECAUTIONS and PATIENT INFORMATION].