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Talk to your doctor if you’re pregnant or planning to become pregnant. When the drug leaves the body, it does so by being filtered out through a specific pathway in the liver.

Viagra begins to work within about an hour and the effects can last for up to four hours. As you get older, Viagra leaves your body more slowly. As a result, a higher amount of a drug stays in your body for a longer time.

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An interaction is when a substance changes the way a drug works. Over half of all men with impotence are thought to have some physical (medical) cause. You do not need to say why you want to talk to the pharmacist, just that you would like to have a quick word. Oh, I haven't ever taken it, but I think the drug that tonyad mentioned is Cisapride, which got pulled for causing (I think) strokes? Some medicines cannot be taken with VIAGRA connect. You should talk to your pharmacist or doctor, who can tell you if the medicines you are taking can be taken with VIAGRA connect. Please read the Patient Information Leaflet for more information. A: When taking more than one medication, it is important to make sure there are no drug interactions.

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The most common side effects of Viagra include headache, facial flushing, and upset stomach. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. These individuals should have no more than 25 milligrams (mg) of Viagra at a time, and not more often than every 48 hours. History Initially, Viagra was designed by Pfizer scientists working in the U. In fact, some of these side effects (such as high blood pressure) can be attributed to enjoying a healthy sex life as a result of taking Viagra.

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Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice. Furthermore, it was only possible that this side effect was related to treatment and a causal relationship to Viagra was uncertain. 24, are believed to be the first confirmation in humans that sildenafil has a direct effect on the heart.  Previous research by Kass and his team showed that sildenafil had such effects in mice, blocking the short-term effects of hormonal stress in the heart.  Related studies by the group also showed that sildenafil prevents and reverses the long-term effects in the heart from chronic high blood pressure.  Moreover, Kass adds, the latest Hopkins results confirm that sildenafil helps control heart function only when the heart is under duress, but has little impact under normal conditions. It is still known all over the globe and some herbal supplements even market themselves as the "herbal Viagra." It relaxes the muscles, and increases blood flow in particular areas of the body, and common side effects may include warmth or redness in the face, chest, and neck, stuffy nose, headache, memory problems, upset stomach and back pain. Again, now that the initial curiosity factor has disappeared, it is unclear how successful sexual dysfunction medication really is. HOW SUPPLIED Dosage Forms And Strengths VIAGRA is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or 100 mg of sildenafil. Its effect is more potent on PDE5 than on other known phosphodiesterases (10-fold for PDE6, > 80-fold for PDE1, > 700-fold for PDE2, PDE3, PDE4, PDE7, PDE8, PDE9, PDE10, and PDE11). Because Viagra dilates the blood vessels and can reduce the blood pressure, it may increase the blood pressure-lowering effect (hypotension) caused by enalapril and Betapace.