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Jen Marsico, RPh Q: I am 66 years old with chronic hypertension controlled with medications. Sildenafil citrate's chemical formula is C22H30N6O4S. If you experience chest pain, dizziness, or nausea during sex, seek immediate medical help.

General You can take this drug with or without food. Sildenafil enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. This does depend on the individual, but this is the case for most men.

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Cardiovascular: angina pectoris, AV block, migraine, syncope, tachycardia, palpitation, hypotension, postural hypotension, myocardial ischemia, cerebral thrombosis, cardiac arrest, heart failure, abnormal electrocardiogram, cardiomyopathy. Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.

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For example, Sildenafil (Viagra) and Tadalafil (Cialis). The patent for Viagra (sildenafil) will not expire until 2012; therefore, no generic, less expensive form is currently available.

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Be very cautious about purchasing a drug claiming to be the generic. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), the researcher says.  This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart.  PDE5A is also the biological pathway blocked in the penis by sildenafil to promote the relaxation of blood vessels and maintain erections.  Funding for this study was provided by the National Institutes of Health (NIH), the Peter Belfer Laboratory Foundation and the Bernard Family Foundation.  The makers of the drug had no involvement in the design or support of the research. Combination With Other PDE5 Inhibitors Or Other Erectile Dysfunction Therapies The safety and efficacy of combinations of VIAGRA with other PDE5 Inhibitors, including REVATIO or other pulmonary arterial hypertension (PAH) treatments containing sildenafil, or other treatments for erectile dysfunction have not been studied. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). Do not take Viagra if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". And he really needs to take a shower before going and eat something....so I bought the Laugh and Learn about Childbirth DVD. Disclaimer: Our goal is to provide you with the most relevant and current information. Read More Hi I had a similar experience had uterus and cervix removed, already knew I had problem w cysts on ovaries and yes one year later back in for ovaries and tubes out. its common drs try to preserve ovaries as yes once gone you are thrown into a automatic menopause not gentley glided into it as nature intends, then you need to decide about bio identical hormone replacement. Arruda-Olson AM, Mahoney DW, Nehra A, Leckel M, Pellikka PA "Cardiovascular effects of sildenafil during exercise in men with known or probable coronary artery disease: a randomized crossover trial." JAMA 287 (2002): 719-25 18. Pregnant women, Lactating mothers can’t use Female Viagra Women with liver and or kidney problems should only take a 25mg dosage at a time Women who are taking alpha-blockers should only take a 25mg dosage at a time four hours after taking their alpha blockers medication How Should You Take Product Name?