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Other drugs may interact with sildenafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Nitric oxide also opens the blood vessels throughout the body, which can cause decreased blood pressure. To investigate further the regulation of E2F by cyclin-dependent kinases, we have extended our studies to include additional cyclins and E2F family members. Other phosphodiesterase inhibitors include Levitra (vardenafil) and Cialis (tadalafil). Following a review of the data from these first 4 subjects (details provided below), the VIAGRA dose was reduced to 25 mg.

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