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A: Taking Viagra twice a day is not necessarily a problem for some people. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. The longer cGMP persists, the more prolonged the engorgement of the penis.Take the Impotence (ED) Quiz Impotence (ED) Slideshow Pictures Unzip Your Sex Life Drug Description Find Lowest Prices on VIAGRA® (sildenafil citrate) Tablets DESCRIPTION VIAGRA (sildenafil citrate), an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). FSIAD has also been referred to as hypoactive sexual desire disorder (HSDD). Hypersensitivity reactions have been reported, including rash and urticaria [see ADVERSE REACTIONS]. The generic company, TEVA pharmaceuticals, has already submitted an application to manufacture a generic Viagra that has already received tentative approval by the FDA.

Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment Of Fertility Carcinogenesis Sildenafil was not carcinogenic when administered to rats for 24 months at a dose resulting in total systemic drug exposure (AUCs) for unbound sildenafil and its major metabolite of 29-and 42-times, for male and female rats, respectively, the exposures observed in human males given the Maximum Recommended Human Dose (MRHD) of 100 mg. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.

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In a study of healthy male volunteers, co-administration of sildenafil at steady state (80 mg t.i.d.) with endothelin receptor antagonist bosentan (a moderate inducer of CYP3A4, CYP2C9 and possibly of CYP2C19) at steady state (125 mg b.i.d.) resulted in a 63% decrease of sildenafil AUC and a 55% decrease in sildenafil Cmax . Michelle McDermott, PharmD Q: My urologist has prescribed 100 mg of Viagra for my erectile dysfunction. Zrenner E "No cause for alarm over retinal side-effects of sildenafil." Lancet 353 (1999): 340-1 45. Increased testosterone levels increases the libido It boosts sexual recall It increases blood flow to the female genitalia hence increasing its sensitivity to touch making it easier to stimulate It increases the intensity and the number of orgasms leading to more sexual satisfaction How Does Female Viagra Work?

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No overall differences in safety or efficacy were observed between older ( > 65 years of age) and younger ( < 65 years of age) subjects. Patients with cardiovascular disease could have additional side effects from Viagra, especially in combination with sexual activity.

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This can result in the drug building up to toxic levels in the body. It is not possible to determine whether these events were directly related to Viagra. You should be aware never to take more than the recommended Viagra dose without consulting a doctor, and to avoid mixing it with similar PDE5 inhibitors as this can increase the risk of unwanted Viagra side effects. These patients had erectile dysfunction at baseline that was characterized by median categorical scores of 2 (a few times) on principal IIEF questions. Grapefruit and grapefruit juice may interact with sildenafil and lead to unwanted side effects. 24, are believed to be the first confirmation in humans that sildenafil has a direct effect on the heart.  Previous research by Kass and his team showed that sildenafil had such effects in mice, blocking the short-term effects of hormonal stress in the heart.  Related studies by the group also showed that sildenafil prevents and reverses the long-term effects in the heart from chronic high blood pressure.  Moreover, Kass adds, the latest Hopkins results confirm that sildenafil helps control heart function only when the heart is under duress, but has little impact under normal conditions. When the drug leaves the body, it does so by being filtered out through a specific pathway in the liver. This is because the fat in your digestive system causes the medication to enter your blood more slowly. Read More In 2002 our family physician gave my husband a prescription for viagra 50 mg. Viagra overdose A Viagra overdose can be serious. To make sure Viagra is safe for you, tell your doctor if you have ever had: heart disease or heart rhythm problems, coronary artery disease; a heart attack, stroke, or congestive heart failure; high or low blood pressure; liver or kidney disease; a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; a bleeding disorder such as hemophilia; a stomach ulcer; retinitis pigmentosa (an inherited condition of the eye); a physical deformity of the penis (such as Peyronie's disease); or if you have been told you should not have sexual intercourse for health reasons. VIAGRA may affect the way other medicines work, and other medicines may affect the way VIAGRA works causing side effects. This allows your pharmacist to keep a complete record of all your prescription drugs and advise you about drug interactions and side effects. If you’ve had certain heart problems in the last 6 months, ask your doctor whether this drug is safe for you. Some people may also have ringing in their ears (tinnitus) or dizziness.